Biclustering of Gene Expression Data by Correlation-Based Scatter Search
نویسندگان
چکیده
منابع مشابه
Seed-Based Biclustering of Gene Expression Data
BACKGROUND Accumulated biological research outcomes show that biological functions do not depend on individual genes, but on complex gene networks. Microarray data are widely used to cluster genes according to their expression levels across experimental conditions. However, functionally related genes generally do not show coherent expression across all conditions since any given cellular proces...
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Co-regulation is a common phenomenon in gene expression. Finding positively and negatively co-regulated gene clusters from gene expression data is a real need. Existing techniques based on global similarity are unable to detect true upand down-regulated gene clusters. This paper presents an expression pattern based biclustering technique, CoBi, for grouping both positively and negatively regula...
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Résumé. L’analyse des données d’expression de génes dans les fragments d’ADN est un outil important utilisé dans la recherche genomique dont les objectifs principaux s’étendent de l’étude du caractére fonctionnel des génes spécifiques et leur participation dans les processus biologiques à la reconstruction de conditions des maladies et leur pronostique. Les données d’expression des génes sont a...
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ژورنال
عنوان ژورنال: BioData Mining
سال: 2011
ISSN: 1756-0381
DOI: 10.1186/1756-0381-4-3